一种简易的小动物一氧化氮吸入系统的研制

作者自行设计一套小动物一氧化氮吸入系统，该系统主要包括有机玻璃舱，采气泵，流量计，ＮＯ／Ｎ２混和气体，纯氧，氮氧化物分析仪，Ｏ２，ＣＯ２监测仪。实验过程中，将６－７只大鼠置于舱内分别吸入２０ｐｐｍ，４０ｐｐｍ，８０ｐｐｍ和ＮＯ８ｈ，每２０ｍｉｎ记录一次舱内ＮＯ，ＮＯ２，Ｏ２和ＣＯ２的浓度值。结果表明舱内的实测ＮＯ浓度与实验所设计的ＮＯ浓度相近，舱内氧浓度与空气中的氧浓度相似，ＮＯ和ＣＯ２最大浓度分

A SIMPLE NITRIC OXIDE EXPOSURE SYSTEM FOR SMALL ANIMALS

A nitric oxide exposing system was designed for experimental research, which consist of equipments such as plexiglass chamber, blower, flowmeter, NO/N2 cylinder, pure O2 cylinder, NOx analyzer, and O2/CO2 monitor. The efficacy of the whole system has been verified through our practice as shown by the following results: measured NO inside the chamber were close to designed NO concentration, measured O2 concentrations in the chamber were similar to that of the atmosphere, and the highest nitrogen dioxide (NO2) and carbon dioxide (CO2) concentrations were lower than 3 ppm and 0.3% respectively. The experimental facility is simple in construction, easy to be operated and convenient for research on effects and toxicity of long-term inhaled nitric oxide in small animals.