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吗啡成瘾大鼠胰腺外分泌的变化
引用本文:姜振玲,朱文玉.吗啡成瘾大鼠胰腺外分泌的变化[J].中国应用生理学杂志,1997,13(1):43-45.
作者姓名:姜振玲  朱文玉
作者单位:北京医科大学生理学系
摘    要:本实验采用急性吗啡成瘾法,观察了吗啡成瘾大鼠在整体胰导管引流和离体胰片灌流条件下,胰腺对CCK8刺激的反应。结果如下:(1)吗啡成瘾大鼠对CCK8诱导的淀粉酶分泌反应降低;(2)吗啡成瘾大鼠胰腺组织中淀粉酶含量降低。提示吗啡成瘾大鼠胰淀粉酶合成受到抑制。

关 键 词:吗啡  吗啡成瘾大鼠  胰淀粉酶

CHANGES OF EXTERNAL SECRETION OF PANCREAS IN MORPHINE DEPENDENT RAT
Jiang Zhenling,Zhu Wenyu.CHANGES OF EXTERNAL SECRETION OF PANCREAS IN MORPHINE DEPENDENT RAT[J].Chinese Journal of Applied Physiology,1997,13(1):43-45.
Authors:Jiang Zhenling  Zhu Wenyu
Institution:Department of Physiology, Beijing Medical University.
Abstract:The present study was done both in vivo by cannulating pancreatic duct of morphine dependent rats and in vitro using perfused pancreatic slices from morphine dependent rats. The results were as follows: (1) In morphine dependent rat the pancreatic amylase secretion induced by CCK 8 was significantly declined; (2) Amylase content of pancreatic tissue in morphine dependent rats was lower than that of normal rats. It is suggested that the synthesis of amylase in morphine dependent rat pancreas may be inhibited.
Keywords:morphine  morphine  dependent rat  pancreatic amylase  
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