Chemical Constituents from the Stems of Excoecaria acertiflia |
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| Authors: | Sheng‐Zhuo Huang Huai‐Rong Luo Qing‐Yun Ma Hua Peng Hao‐Fu Dai Jun Zhou You‐Xing Zhao |
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| Institution: | 1. Hainan Key Laboratory for Research and Development of Natural Product from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, P.?R. China, (phone/fax: +86‐898‐66989095);2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.?R. China |
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| Abstract: | Six new compounds, including two diterpenoids excocarinols F and G ( 1 and 2 , resp.), two carotane (daucane) sesquiterpenoids excoecafolinols A and B ( 3 and 4 , resp.), one lignanoid compound, excoecanol A ( 5 ), and one simple phenol, excoecanol B ( 6 ), together with 17 known compounds, were isolated from the BuOH extract of Excoecaria acerifolia Didr . stems. Their structures were elucidated through the analysis of the spectroscopic data. The AChE‐inhibitory activities of 17 compounds were evaluated and revealed that four of them possessed moderate inhibitory activities against AChE. |
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| Keywords: | Excoecaria acerifolia Diterpenoids Sesquiterpenoids AChE Inhibitory activity |
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