| 致病性念珠菌对常见抗真菌药物的耐药性研究进展 |
| |
| 引用本文： | 张浩,刘伟.致病性念珠菌对常见抗真菌药物的耐药性研究进展[J].菌物学报,2020,39(11):2109-2119. |
| |
| 作者姓名： | 张浩 刘伟 |
| |
| 作者单位： | 1.北京大学第一医院皮肤性病科 国家皮肤与免疫疾病临床医学研究中心 北京大学真菌和真菌病研究中心 皮肤病分子诊断北京市重点实验室 北京 1000342.江西省儿童医院皮肤科 江西 南昌 330006 |
| |
| 基金项目： | 国家科技重大专项;科技部艾滋病;国家传染病防治科技重大专项;国家自然科学基金 |
| |
| 摘 要： | 近年来,致病性念珠菌感染引起的侵袭性念珠菌病患者人数逐年增多。白念珠菌仍是引起感染的主要致病菌,但是由非白念念珠菌引起的感染比例显著升高。致病性念珠菌对常见抗真菌药物的耐药现象呈上升趋势,这是导致临床治疗其所致的侵袭性感染失败的重要原因之一。本文就致病性念珠菌耐药性的流行病学以及其耐药机制方面的研究进展进行了介绍。
|
| 关 键 词： | 念珠菌 耐药性 耐药机制 |
| 收稿时间： | 2020-06-02 |
Research progress on resistance of pathogenic Candida species to common antifungal drugs |
| |
| Authors: | ZHANG Hao LIU Wei |
| |
| Institution: | 1. Department of Dermatology, Peking University First Hospital, National Clinical Research Center for Skin and Immune Diseases, Research Center for Medical Mycology, Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing 100034, China2. Department of Dermatology, Jiangxi Provincial Children’s Hospital, Nanchang, Jiangxi 330006, China |
| |
| Abstract: | In recent years, the number of patients suffering from invasive candidiasis caused by pathogenic Candida species has increased. Although Candida albicans remains the most common pathogen, non-albicans Candida infections have increased significantly. The resistance of pathogenic Candida species to common antifungal drugs trends to rise, causing the failure of clinical treatment of infection. In this review, the research progress on the epidemiology of drug-resistance and resistant mechanisms of pathogenic Candida species are described. |
| |
| Keywords: | Candida drug resistance resistance mechanisms |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《菌物学报》浏览原始摘要信息 |
| 点击此处可从《菌物学报》下载免费的PDF全文 |
|
