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The Quinone Methide Aurin Is a Heat Shock Response Inducer That Causes Proteotoxic Stress and Noxa-dependent Apoptosis in Malignant Melanoma Cells
Authors:Angela L Davis  Shuxi Qiao  Jessica L Lesson  Montserrat Rojo de la Vega  Sophia L Park  Carol M Seanez  Vijay Gokhale  Christopher M Cabello  Georg T Wondrak
Institution:From the Department of Pharmacology and Toxicology, College of Pharmacy and Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724
Abstract:
Keywords:Apoptosis  Drug Discovery  Heat Shock Protein 90 (Hsp90)  Melanoma  Oxidative Stress  Noxa  Aurin  Heat Shock Response  Proteotoxic Stress
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