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Molecular genetic analysis of Dongzhou-period ancient human of Helingeer in Inner Mongolia, China
Authors:Yuqin Fu  Chengzhi Xie  Han Zhao  Xuelian Xu  Yinqiu Cui  Quanchao Zhang  Hui Zhou  Hong Zhu
Institution:1. Ancient DNA Laboratory, Research Center for Chinese Frontier Archaeology, Jilin University, Changchun, 130012, China
2. College of Life Science, Jilin University, Changchun, 130023, China
3. College of Life Science, Jilin Agricultural University, Changchun, 130118, China
Abstract:The mtDNA hypervariable region I (HVR-I) of 10 ancient individuals from Dongzhou-period ancient human populations in Helingeer county of Inner Mongolia were amplified and sequenced to investigate the genetic structure. The relationships between the ancient population and related extant populations, as well as its possible origin at the molecular level, were also studied. Moreover, phylogenetic analysis and multi-dimensional scaling analysis were also performed based on the mtDNA data of the ancient population in Helingeer and the related Eurasian population. The results showed that the ancient population in Helingeer were closer to the northern Asian populations than to the other compared populations in matrilineal lineage. Combining the research results of archaeology and anthropology as well as molecular biology, we inferred that they were nomads who migrated from Mongolia plateau and cis-Baikal region to Helingeer in Inner Mongolia, China.
Keywords:ancient DNA  mtDNA  genetic structure  phylogenetic analysis
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