Development of human antibody fragments using antibody phage display for the detection and diagnosis of Venezuelan equine encephalitis virus (VEEV) |
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| Authors: | Martina Inga Kirsch Birgit Hülseweh Christoph Nacke Torsten Rülker Thomas Schirrmann Hans-Jürgen Marschall Michael Hust Stefan Dübel |
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| Institution: | 1.Abteilung Biotechnologie, Institut für Biochemie und Biotechnologie,Technische Universit?t Braunschweig,Braunschweig,Germany;2.Armed Forces Scientific Institute for Protection Technologies – NBC Protection (WIS),Munster,Germany |
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| Abstract: | Background Venezuelan equine encephalitis virus (VEEV) belongs to the Alphavirus group. Several species of this family are also pathogenic
to humans and are recognized as potential agents of biological warfare and terrorism. The objective of this work was the generation
of recombinant antibodies for the detection of VEEV after a potential bioterrorism assault or an natural outbreak of VEEV. |
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