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PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol
Authors:Email author" target="_blank">David?G?LevittEmail author
Institution:(1) Department of Physiology, , 6-125 Jackson Hall, 321 Church St, S. E., Minneapolis, MN 55455, USA
Abstract:

Background  

A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific solutes, required specification of a large number of parameters and have not been designed for general use.
Keywords:
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