Modeling <Emphasis Type="Italic">Neisseria meningitidis</Emphasis> metabolism: from genome to metabolic fluxes |
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| Authors: | Gino JE Baart Bert Zomer Alex de Haan Leo A van der Pol E Coen Beuvery Johannes Tramper Dirk E Martens |
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| Institution: | (1) Unit Research &; Development, Netherlands Vaccine Institute (NVI), 457, 3720, AL Bilthoven, The Netherlands;(2) PAT Consultancy, Kerkstraat, 66, 4132 BG Vianen, The Netherlands;(3) Food and Bioprocess Engineering Group, Wageningen University, 8129, 6700 EV Wageningen, The Netherlands |
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| Abstract: | Background
Neisseria meningitidis is a human pathogen that can infect diverse sites within the human host. The major diseases caused by N. meningitidis are responsible for death and disability, especially in young infants. In general, most of the recent work on N. meningitidis focuses on potential antigens and their functions, immunogenicity, and pathogenicity mechanisms. Very little work has been
carried out on Neisseria primary metabolism over the past 25 years. |
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