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Comparative analysis reveals signatures of differentiation amid genomic polymorphism in Lake Malawi cichlids
Authors:Yong-Hwee E Loh  Lee S Katz  Meryl C Mims  Thomas D Kocher  Soojin V Yi  J Todd Streelman
Institution:(1) School of Biology, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, Georgia 30332, USA;(2) Department of Biology, University of Maryland, College Park, Maryland, 20742, USA
Abstract:

Background  

Cichlid fish from East Africa are remarkable for phenotypic and behavioral diversity on a backdrop of genomic similarity. In 2006, the Joint Genome Institute completed low coverage survey sequencing of the genomes of five phenotypically and ecologically diverse Lake Malawi species. We report a computational and comparative analysis of these data that provides insight into the mechanisms that make closely related species different from one another.
Keywords:
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