Identification of ATP binding residues of a protein from its primary sequence |
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Authors: | Jagat S Chauhan Nitish K Mishra and Gajendra PS Raghava |
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Institution: | (1) Institute of Microbial Technology, Chandigarh, India |
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Abstract: | Background One of the major challenges in post-genomic era is to provide functional annotations for large number of proteins arising
from genome sequencing projects. The function of many proteins depends on their interaction with small molecules or ligands.
ATP is one such important ligand that plays critical role as a coenzyme in the functionality of many proteins. There is a
need to develop method for identifying ATP interacting residues in a ATP binding proteins (ABPs), in order to understand mechanism
of protein-ligands interaction. |
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