Modifying the DPClus algorithm for identifying protein complexes based on new topological structures |
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| Authors: | Min Li Jian-er Chen Jian-xin Wang Bin Hu Gang Chen |
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| Institution: | (1) School of Information Science and Engineering, Central South University, Changsha, Hunan, 410083, PR China;(2) Department of Computer Science, Texas A&M University, College Station, Texas 77843, USA |
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| Abstract: | Background Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the
size of protein-protein interaction set increases, a general trend is to represent the interactions as a network and to develop
effective algorithms to detect significant complexes in such networks. |
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