Pash 3.0: A versatile software package for read mapping and integrative analysis of genomic and epigenomic variation using massively parallel DNA sequencing |
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Authors: | Cristian Coarfa Fuli Yu Christopher A Miller Zuozhou Chen R Alan Harris Aleksandar Milosavljevic |
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Institution: | 1.Department of Molecular and Human Genetics,Baylor College of Medicine,Houston,USA;2.The Human Genome Sequencing Center,Baylor College of Medicine,Houston,USA |
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Abstract: | Background Massively parallel sequencing readouts of epigenomic assays are enabling integrative genome-wide analyses of genomic and epigenomic
variation. Pash 3.0 performs sequence comparison and read mapping and can be employed as a module within diverse configurable
analysis pipelines, including ChIP-Seq and methylome mapping by whole-genome bisulfite sequencing. |
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