伴血嗜酸性粒细胞增高的腹痛临床分析

目的探讨伴血嗜酸性粒细胞(Eosinophil,EOS)增高的腹痛病因、诊断、治疗方法。方法对我院31例伴血EOS增高的腹痛患者的临床表现、实验室检查、特殊检查结果进行分析,总结伴血EOS增高的腹痛病因及治疗方法。结果伴血EOS升高的腹痛的病因以寄生虫、变态反应性疾病为主,此外亦有可能为嗜酸性胃肠炎(Eosinophilic Gastroenteritis,EG)、恶性肿瘤、药物所致,少见病因为炎症性肠病、慢性胰腺炎、特发性嗜酸性细胞增多症(Idiopathic Hypereosinophilic Syndrome,HES)等。大部分EOS升高的腹痛以治疗原发病为主,EG及HES以激素治疗为主。结论伴血EOS升高的腹痛病因多样,大部分病因治疗原发病后EOS可自行下降,EG及HES以激素治疗效果好,作用迅速。

Clinical analysis of abdominal pain with increased blood eosinophil

Objective To investigate the aetiology,diagnosis, misdiagnosis and therapy of abdominal pain with increased blood eosinophil. Methods 31 patients of abdominal pain with increased blood eosinophil in our hospital were studied retrospectively. Results Parasitic infections,allergic diseases were the major causes of abdominal pain with elevated eosinophils. There were also likely to eosinophilic gastroenteritis（EG）,malignancy, drug-induced. Inflammatory bowel disease, chronic pancreatitis, idiopathic hypereosinophilic syndrome（HES） were rare causes. Most of abdominal pain with increased EOS were mainly treatment of the primary disease. Treatment with steroid was recommended for EG and HES. Conclusion The causes of abdominal pain with elevated eosinophils are varied. Most of eosinophils are free to decline after the treatments of primary diseases. Steroid acts quickly and leads to perfect result for EG and HES.