血清电解质紊乱对ICU慢性阻塞性肺疾病患者预后的影响

目的探讨血清电解质紊乱对慢性阻塞性肺疾病（COPD）预后的影响。方法将广西医科大学第一附属医院ICU2007年7月~2008年1月收治的213例慢性阻塞性肺疾病患者,按血清电解质水平分为非电解质紊乱组86例和电解质紊乱组127例,分析不同电解质水平与COPD预后之间的关系。结果两组患者年龄、性别无显著差异性,两组的住院时间、发生酸碱失衡、接受机械通气治疗时间及病死率比较差异有显著性（P〈0.05）。电解质紊乱组经治疗后,得以纠正者治疗有效率高于纠正无效者,两者差异有统计学意义。结论 COPD合并电解质紊乱较非电解质紊乱患者的住院时间及入住ICU接受机械通气治疗时间长,前者病死率较后者高。电解质紊乱可以作为判断慢性阻塞性肺疾病病情预后的指标之一。

The Influence of Electrolytes Disorder on the Prognosis of Patients with Chronic Obstructive Pulmonary disease

Objective To investigate the influence of the serum electrolyte disturbance on the prognosis of pa-tients with chronic obstructive pulmonary disease（COPD）. Methods 213 cases of COPD treated during the July 2007 to the December 2008 were collected from the First Affiliated Hospital of Guangxi Medical University.Ac-cording to the occurrence of electrolyte disorder,they were divided into two groups,86 patients with electrolyte dis-order and the rest 127 without electrolyte disorder.We analyzed retrospectively and compared the influence of the electrolyte disorder on the prognosis of COPD between the two groups. Results There were significant differ-ences in the hospital stay,the incidence of acid-base disorders,the length of mechanical ventilation in ICU and the mortality between the COPD with electrolytes disorder group and the COPD without electrolytes disorder group, while no significant difference in the baseline such as age and gender between the two groups（P0.05）.The treat-ment of patients with cured electrolyte disorder had more effective than those with recurrent electrolyte disorder in the COPD with the electrolytes disorder group. Conclusion The COPD with electrolyte disorder group had lon-ger hospital stay and higher mortality than the COPD without electrolyte disorder group.Electrolyte disorder can be established as one of indicators to the prognosis of COPD.