| 石杉碱甲对氧自由基的影响 |
| |
| 引用本文： | 周永其,邓湘平,顾振纶.石杉碱甲对氧自由基的影响[J].中国野生植物资源,2004,23(2):44-45. |
| |
| 作者姓名： | 周永其 邓湘平 顾振纶 |
| |
| 作者单位： | 1. 太仓市第一人民医院,江苏,太仓,215400
2. 苏州大学医学院药理教研室,苏州中药研究所,江苏,苏州,215007 |
| |
| 摘 要： | 目的:研究石杉碱甲对氧自由基的影响,探讨石杉碱甲抗老年性痴呆的机制.方法:按50 mg/kg·d给大鼠皮下注射D-半乳糖6周后,按石杉碱甲0.1mg/kg·d、0.2mg/kg·d给药2周,检测血清和脑组织中SOD活力和MDA含量.结果:石杉碱甲能明显提高大鼠血清和脑组织中SOD的活力,同时降低MDA的含量.结论:加快氧自由基的清除、减少自由基损伤是石杉碱甲抗老年性痴呆的机制之一.
|
| 关 键 词： | 石杉碱甲 D-半乳糖 |
| 修稿时间： | 2003年5月28日 |
The Effects of Huperzine-A on Oxygen-derived Free Radicals |
| |
| Zhou Yongqi ,Deng Xiangping ,Gu Zhenlun.The Effects of Huperzine-A on Oxygen-derived Free Radicals[J].Chinese Wild Plant Resources,2004,23(2):44-45. |
| |
| Authors: | Zhou Yongqi Deng Xiangping Gu Zhenlun |
| |
| Institution: | Zhou Yongqi 1,Deng Xiangping 2,Gu Zhenlun 2 |
| |
| Abstract: | Objective: To study the anti dementia mechanism of Huperzine A. Method:The activities of SOD and contents of MDA in rat's serum and brain were measured after the rats were injected D galactose 6weeks and were administrated Hup A 2 weeks. Results: Hup A can improve the SOD activity and decrease the MDA content in rat's serum and brain. Conclusion: Facilitating the elimination and reducing the demage of oxygen derived free radidicals is one of the anti dementia mechanisms of Huperzine A. |
| |
| Keywords: | SOD MDA |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
