| 传统光学相干断层成像:软骨双折射特性的研究 |
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| 引用本文： | 冯音琦.传统光学相干断层成像:软骨双折射特性的研究[J].激光生物学报,2006,15(6):655-660. |
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| 作者姓名： | 冯音琦 |
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| 作者单位： | 北京石油化工学院,光机电装备技术北京市重点实验室,北京,102617 |
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| 基金项目： | The grants from an advanced program of Beijing science and technology foundation for roturned scholars and students in 2005; agenernal Science an Technology devlopment program of Beijing Ministry of Education( NO. KM20061001 ＞ 005 ) |
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| 摘 要： | 传统光学相干断层成像可实现无损伤在体检测，具有较高的分辨率和灵敏度。获取生物组织的双折射信息可望是其应用之一。本文用传统光学相干断层成像系统以动物模型对关节软骨进行了研究，对软骨组织的传统光学相干断层图像的层结构随脱水和机械作用的变化进行了分析。结果表明，传统光学相干断层成像系统在一定程度上可用于监测由其胶原质纤维排列决定的软骨组织的双折射和密度。
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| 关 键 词： | 光学相干断层成像 软骨组织 双折射 |
| 文章编号： | 1007-7146(2006)06-0655-06 |
| 收稿时间： | 2006/2/24 |
| 修稿时间： | 2006年2月24日 |
The Study on Birefringence Feature of Cartilage by Conventional Optical Coherence Tomography |
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| FENG Yin-qi.The Study on Birefringence Feature of Cartilage by Conventional Optical Coherence Tomography[J].ACTA Laser Biology Sinica,2006,15(6):655-660. |
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| Authors: | FENG Yin-qi |
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| Abstract: | The conventional optical coherence tomography (COCT) can realize non-invasive and in vivo measurement with high spatial resolution and sensitivity. One of its applications is possible for obtaining birefringence information of biological tissues. In this paper, by using of a COCT system, articular cartilages with an animal model are studied. Layer structures formed on the COCT images are investigated in theory and experiments. The changes of layer structures of cartilage tissues on the COCT images with dehydration and mechanical action are analyzed, which shows that a COCT system may be capable of monitoring cartilage birefringence determined by the collagen fibre alignment and its packing density. |
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| Keywords: | Optical Coherence Tomography cartilage tissue birefringence |
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