程序性细胞死亡及其激光FCM检测方法

程序性细胞死亡是细胞生理性死亡最常见的形式，是细胞对其周围环境信号的主动反应。在此过程中细胞发生一系列特征性的变化，一些基因表达参与或调控此过程。ＦＣＭ是检测研究程序性细胞死亡的重要手段。诱导肿瘤细胞发生程序性死亡是肿瘤治疗的新途径。程序性细胞死亡的检测对肿瘤治疗研究及其临床疗效判断都有其应用前景。

APOPTOSIS AND ITS LASER-FCM MEASUREMENT

Apoptosis is the most common form of cell death in physiological condition,and is an active reac- tion of cells to surrounding signals. There are a series of specific morphological and biochemical events in theprocess. Some genes are expressed in cells undergoing apoptosis or their modulation affects the process. FCM is an important technique for quantitative analysis of apoptosis. To induce apoptosis can open newstrategies for improving cancer chemotherapy. Early detection of apoptosis cells in clinical patient tumorswould be of great value to predict the outcome of treatment protocols.