肺心病患者血清甲状腺激素的变化

本文分析30例慢性肺心病心衰并呼衰患者(心衰并呼衰组)及30例慢性肺心病心衰无呼衰患者(心衰无呼哀组)和慢性肺心病死亡组的血清甲状腺激素水平。结果表明心衰并呼衰组T_3、T_4水平均值显著低于心衰无呼衰组和健康组,心衰无呼衰组T_3水平均值显著低于健康组,肺心病死亡组T_3、T_4水平均值显著低于存活组,并发现血清T_3、T_4水平与动脉血氧分压(PaO_2)呈正相关。作者认为T_3明显降低是重症肺心病的损伤性结果,预示病情严重,预后差。而T_4明显下降,可能是死亡的信号之一。

ACHANGE OF SERUM THYROXIN OF CHRONIC COR PULMONALE

Serum level of thyroxin was measured in 30 patients with chronic cor pulmonale complicated heart failure and respiratory failure (The heart failure group with respiratory failure ) , 30 patients with chronic cor pulmonale complicated heart failure without respiratory failure ( The heart failure group without respiratory failure) and the death group. The mean levels of T3 and T4 were significantly lower in the heart failure group with respiratory failure than in the heart failure group withont respiratory failure and the controls. The mean levels of T3 and T4 weve significantly lower in the death group than in the survival group. Serum levels of T3 and T4 showed a positive correlation with Partial Pressure of oxygen in arterial blood(PaO2).Author considered that the apparent reduction of T3 was as a result of injury of severe Pulmonary Heart Disease, which suggested exacerbation of disease and unfavourable prognosis. The apparent reduction of T4 might be a signal of death.