Pioneering studies of the "morning-after" pill |
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Authors: | Kunjappu Mary J |
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Institution: | Department of Molecular, Cellular, and Developmental Biology, Graduate School of Arts and Sciences, Yale University, 266 Whitney Avenue, New Haven, CT 06511, USA. mary.kunjappu@yale.edu |
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Abstract: | Yale School of Medicine produced the first proof-of-concept study on the viability of a "morning-after" pill for human use. This study was a result of a fruitful collaboration between a pair of Yale scientists, Drs. John M. Morris and Gertrude van Wagenen, who sought a non-abortion, post-coital contraceptive. They tested a variety of hormones, hormone-based synthetic drugs, and other compounds in monkeys in an effort to uncover a compound that was non-toxic but highly effective. Unfortunately, although they were unable to identify such a drug, their initial studies inspired other scientists to further pursue the concept of a "morning-after" pill, leading to the development of Food and Drug Administration (FDA)-approved emergency contraceptives. |
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Keywords: | emergency contraception "morning-after" pill estrogenic compounds diethylstilbestrol ethinyl estradiol |
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