| DNA损伤与细胞周期调控 |
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| 引用本文： | 于廷曦,朱应葆,童坦君.DNA损伤与细胞周期调控[J].生物化学与生物物理进展,1999,26(4):351-354. |
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| 作者姓名： | 于廷曦 朱应葆 童坦君 |
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| 作者单位： | 1. 北京医科大学第三临床医学院,北京100083
2. 北京医科大学生物化学与分子生物学系,北京,100083 |
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| 基金项目： | 国家自然科学基金(39670235、39770409、39770238)和863计划生物领域青年基金资助课题. |
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| 摘 要： | DNA损伤和损伤后修复可引起细胞周期阻滞，这一事件由三个阶段组成：损伤的识别,损伤信号的传递以及细胞周期阻滞.在某些情况，这种细胞周期阻滞会失效.
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| 关 键 词： | DNA损伤，细胞周期阻滞，信号传导 |
| 收稿时间： | 1998/6/22 0:00:00 |
| 修稿时间： | : 1998-06- |
DNA Damage and Cell Cycle Control |
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| YU Ting-Xi,ZHU Ying-Bao and TONG Tan-Jun.DNA Damage and Cell Cycle Control[J].Progress In Biochemistry and Biophysics,1999,26(4):351-354. |
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| Authors: | YU Ting-Xi ZHU Ying-Bao and TONG Tan-Jun |
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| Institution: | The Third School of Clinical Medicine, Beijing Medical University, Beijing 100083,China;The Third School of Clinical Medicine, Beijing Medical University, Beijing 100083,China;Department of Biochemistry and Molecular Biology, Beijing Medical University, Beijing 100083, China |
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| Abstract: | DNA damage and repair of damaged DNA can cause cell cycle arrest. This process is consisted of three periods: recognition of damage domain in the DNA, transduction of damage signal and cell cycle arrest. Sometimes, this kind of cell cycle arrest may be failed. |
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| Keywords: | DNA damage cell cycle arrest signal transduction |
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