| 外源基因在大肠杆菌中表达的研究进展 |
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| 引用本文： | 龙建银,王会信.外源基因在大肠杆菌中表达的研究进展[J].生物化学与生物物理进展,1997,24(2):126-132. |
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| 作者姓名： | 龙建银 王会信 |
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| 作者单位： | 军事医学科学院基础医学研究所，北京100850;军事医学科学院基础医学研究所，北京100850 |
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| 摘 要： | 大肠杆菌是外源基因表达的首选体系.大肠杆菌中外源蛋白可定位于胞内、周质或胞外培养基中.按照重组蛋白的可能命运，综述了最近几年大肠杆菌表达体系的研究进展.
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| 关 键 词： | 大肠杆菌，基因表达，分子伴侣，分泌 |
| 收稿时间： | 1996/4/28 0:00:00 |
| 修稿时间： | 1996/9/24 0:00:00 |
Advances in the Study of Foreign Gene Expression in E.coli |
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| LONG Jianyin and WANG Huixin.Advances in the Study of Foreign Gene Expression in E.coli[J].Progress In Biochemistry and Biophysics,1997,24(2):126-132. |
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| Authors: | LONG Jianyin and WANG Huixin |
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| Institution: | Beijing Institute of Basic Medical Sciences, Beijing 100850, China;Beijing Institute of Basic Medical Sciences, Beijing 100850, China |
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| Abstract: | E.coli is still the first choice of host when foreign gene is expressed. Heterologous proteins could be expressed directly in the cytoplasm, secreted into the periplasmic space or extracellular medium. Recent developments on E.coli expression system are covered, according to the possible destiny of foreign proteins. |
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| Keywords: | E coli gene expression molecular chaperone secretion |
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