532 nm和808 nm激光及其线偏振激光辐照人正常膀胱与膀胱癌组织光学特性

采用双积分球系统和光辐射测量技术的基本原理 ,以及运用生物组织的光学模型 ,研究了 5 32nm和80 8nm激光及其线偏振激光辐照人正常膀胱和膀胱癌组织的光学特性 .结果表明 :膀胱癌组织对同一波长的激光或其线偏振激光的衰减明显较正常膀胱组织的要大 ,膀胱癌组织对 5 32nm和 80 8nm激光的衰减均较其线偏振激光的要略大一些 .膀胱癌组织对 5 32nm和 80 8nm激光及其线偏振激光的衰减明显较正常膀胱组织的要大 .正常膀胱或膀胱癌组织对同一波长的激光及其线偏振激光的折射率均没有明显的差异 ,膀胱癌组织对 5 32nm和80 8nm激光的折射率比正常膀胱的明显要大 .Kubelka Munk二流模型下 ,两种组织对同一波长的激光或其线偏振激光的光学特性均有显著性差异 (P <0 0 1) .同一组织对不同波长的激光及其线偏振激光的光学特性也有显著性差异 (P <0 0 1) ,正常膀胱组织对同一波长的激光及其线偏振激光的光学性有明显差异 ,而膀胱癌组织对同一波长的激光及其线偏振激光的光学特性则没有明显差异 .膀胱癌组织对 5 32nm和 80 8nm激光及其线偏振激光的前向散射通量i (x)、后向散射通量 j (x)、总散射通量I (x)的衰减均较正常膀胱组织的明显要大得多 ,且其i (x)均明显较j (x)要强

Optical Properties of Human Normal Bladder and Bladder Cancer Tissue at 532 nm and 808 nm Laser and Their Linearly Polarized Laser Irradiation In vitro

A double integrating spheres system, basic principle of measuring technology of ray radiation, optical model of biological tissues were used for the study. Optical properties of human normal bladder and bladder cancer tissues at 532 nm and 808 nm laser and their linearly polarized laser irradiation were studied. The results of measurement showed that attenuation of light intensities in human bladder cancer tissue were obviously bigger than one of human normal bladder tissue at a certain wavelength of laser or the linearly polarized laser irradiation. Attenuation of light intensities in human bladder cancer tissue at 532 nm and 808 nm laser was slightly bigger than one of human normal bladder tissue at the linearly polarized laser irradiation. Attenuation of light intensities in human bladder cancer tissue at 532 nm and 808 nm laser and their linearly polarized laser irradiation was obviously bigger than one of human normal bladder tissue at 532 nm and 808 nm laser and their linearly polarized laser irradiation. Refractive index of human normal bladder or human bladder cancer tissue at a certain wavelength of laser and its linearly polarized laser irradiation had not obvious distinction. Refractive index of human normal bladder tissue was obviously bigger than one of human normal bladder tissue at 532 nm and 808 nm laser. Optical properties of all of human normal bladder tissue and bladder cancer tissues in Kubelka Munk two flux model at a certain wavelength of laser or its linearly polarized laser irradiation had prominent distinction ( P <0 01). Optical properties of a certain of tissue at 532 nm and 808 nm laser and their linearly polarized laser irradiation had either prominent distinction ( P <0 01). Optical properties of human normal bladder tissue at a certain wavelength of laser and its linearly polarized laser had obvious distinction. And optical properties of human bladder cancer tissue at a certain wavelength of laser and its linearly polarized laser irradiation had not prominent distinction. Attenuation of all of the forward scattered photon fluxes i(x) , the backward scattered photon fluxes j(x) , the total scattered photon fluxes I(x) of human bladder cancer tissue at 532 nm and 808 nm laser and their linearly polarized laser irradiation is obviously bigger than one of human normal bladder tissue. And that light intensities of their forward scattered photon fluxes i(x) was obviously bigger than one of their backward scattered photon fluxes j(x) .