| 甜味蛋白研究的新进展 |
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| 引用本文： | 吕利群,齐义鹏.甜味蛋白研究的新进展[J].生物化学与生物物理进展,1997,24(1):36-38. |
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| 作者姓名： | 吕利群 齐义鹏 |
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| 作者单位： | 武汉大学病毒研究所, 武汉 430072;武汉大学病毒研究所, 武汉 430072 |
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| 摘 要： | 甜味蛋白(thaumatin)是世界上已知最甜的物质,具有很大的应用前景.Thaumatin的基因核苷酸和蛋白质氨基酸序列都已测定.晶体分析表明它具有高稳定的四级结构.在味蕾小孔中发现了介导thaumatin发生作用的物质.Thaumatin自身的功能仍不清楚.在多种生物中发现了thaumatin类似蛋白质,具有不同的生物活性.用基因工程手段实现了thaumatin在多种原核和真核生物中的表达,但迄今仍未得到理想的基因工程产品.
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| 关 键 词： | 甜味蛋白 Thaumatin 结构域 基因工程 |
| 收稿时间： | 1996/3/12 0:00:00 |
| 修稿时间： | 1996/7/22 0:00:00 |
Recent Progress on the Study of Sweet Protein |
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| LU Liqun and QI Yipeng.Recent Progress on the Study of Sweet Protein[J].Progress In Biochemistry and Biophysics,1997,24(1):36-38. |
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| Authors: | LU Liqun and QI Yipeng |
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| Institution: | Institute of Virology, Wuhan University, Wuhan 430072, China;Institute of Virology, Wuhan University, Wuhan 430072, China |
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| Abstract: | Sweet protein thaumatin is the sweetest substance known so far.Thaumatin has many features that make it attractive to food and feed manufacturers.Its nucleic acid sequence and amino acid sequence have been reported.Structure analysis showed that thaumatin has high stable tertiary structure. The substance mediated between thaumatin and microvilli of the taste bud pores has been found.The exact function of thaumatin and thaumatin like protein is still not clear. Thaumatin has been expressed in some procaryotic and eucaryotic expression systems, but no satisfied products can be got through the way of gene engineering by now. |
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| Keywords: | sweet protein thaumatin domain gene engineering |
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