| 非编码的mRNA |
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| 引用本文： | 罗文琴,袁建刚,强伯勤.非编码的mRNA[J].生物化学与生物物理进展,1998,25(5):387-389. |
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| 作者姓名： | 罗文琴 袁建刚 强伯勤 |
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| 作者单位： | 中国医学科学院基础医学研究所中国协和医科大学基础医学院,医学分子生物学国家重点实验室, 北京 100005;中国医学科学院基础医学研究所中国协和医科大学基础医学院,医学分子生物学国家重点实验室, 北京 100005;中国医学科学院基础医学研究所中国协和医科大学基础医学院,医学分子生物学国家重点实验室, 北京 100005 |
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| 摘 要： | 非编码的mRNA是近年发现的一类不含典型ORF的mRNA.目前已发现或克隆的这类基因主要有：H19基因，XIST基因，XLSIRT基因，His-1基因，bic基因，rox1和rox2基因等.它们与胚胎发育，肿瘤发生及X染色体失活密切相关.
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| 关 键 词： | 非编码的mRNA，H19基因，XIST基因，His-1基因，bic基因，rox1和rox2基因 |
| 收稿时间： | 1998/3/13 0:00:00 |
| 修稿时间： | 1998/6/18 0:00:00 |
Non-coding mRNA |
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| LUO Wen-qin,YUAN Jian-gang and QIANG Bo-qin.Non-coding mRNA[J].Progress In Biochemistry and Biophysics,1998,25(5):387-389. |
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| Authors: | LUO Wen-qin YUAN Jian-gang and QIANG Bo-qin |
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| Institution: | Institute of Basic Medical Science, Chinese Academy of Medical Sciences & Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005, China;Institute of Basic Medical Science, Chinese Academy of Medical Sciences & Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005, China;Institute of Basic Medical Science, Chinese Academy of Medical Sciences & Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing 100005, China |
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| Abstract: | Non-coding mRNA is a kind of newly discovered mRNA. Though spliced and tailed,it does not have any typical ORF. Up to date, several such genes have been cloned: H19 gene, XIST gene, XLSIRT gene, His-1 gene, bic gene, rox1 and rox2 genes. Non-coding mRNA play important roles in the development of embryos, in the inactivation of X chromosome and in the tumorigenesis. |
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| Keywords: | non-coding mRNA H19 gene XIST gene His-1 gene bic gene rox1 gene and rox2 gene |
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