| 超微粒TiO2对U937细胞光杀伤效应及机理研究 |
| |
| 引用本文： | 黄宁平,黄丹,徐敏华,袁春伟.超微粒TiO2对U937细胞光杀伤效应及机理研究[J].生物化学与生物物理进展,1997,24(5):470-473. |
| |
| 作者姓名： | 黄宁平 黄丹 徐敏华 袁春伟 |
| |
| 作者单位： | 东南大学分子与生物分子电子学实验室，南京 210096;南通师范专科学校，南通 226000;东南大学分子与生物分子电子学实验室，南京 210096;东南大学分子与生物分子电子学实验室，南京 210096 |
| |
| 摘 要： | 超微粒TiO2经光催化氧化后对U937白血病细胞有明显的杀伤作用，DNA琼脂糖凝胶电泳图证明了光激发TiO2能够损伤细胞内的DNA，从而导致细胞死亡，提出了一种杀伤癌细胞的新思路.
|
| 关 键 词： | 超微粒TiO2，光催化氧化，U937细胞，活性氧类 |
| 收稿时间： | 9/5/1996 12:00:00 AM |
| 修稿时间： | 1996/12/7 0:00:00 |
The Study of the Photokilling Effect and Mechanism of Ultrafine TiO2 Particles on U937 Cells |
| |
| HUANG Ningping,HUANG Dan,XU Minhua and YUAN Chunwei.The Study of the Photokilling Effect and Mechanism of Ultrafine TiO2 Particles on U937 Cells[J].Progress In Biochemistry and Biophysics,1997,24(5):470-473. |
| |
| Authors: | HUANG Ningping HUANG Dan XU Minhua and YUAN Chunwei |
| |
| Institution: | National Labora-tory of Molecular and Biomolecular Electronics, Southeast University, Nanjing 210096, China;National Labora-tory of Molecular and Biomolecular Electronics, Southeast University, Nanjing 210096, China;National Labora-tory of Molecular and Biomolecular Electronics, Southeast University, Nanjing 210096, China;National Labora-tory of Molecular and Biomolecular Electronics, Southeast University, Nanjing 210096, China |
| |
| Abstract: | The killing effect of photoexcited TiO2 particles on U937 cells has been studied. DNA agarose gel electrophoresis shows that photoexcited TiO2 particles can damage DNA, leading to the death of cells. So a new assumption of the way to kill cancer cells is proposed. |
| |
| Keywords: | ultrafine TiO2 particles(UFP TiO2) photocatalytic killing effect U937 cells reactive oxygen species (ROS) |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《生物化学与生物物理进展》浏览原始摘要信息 |
| 点击此处可从《生物化学与生物物理进展》下载免费的PDF全文 |
