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中国专利基因数据库的创建
引用本文:杨仑,徐朗莱.中国专利基因数据库的创建[J].生物化学与生物物理进展,2006,33(8):800-803.
作者姓名:杨仑  徐朗莱
作者单位:1. 南京农业大学生命科学学院,南京,210095;南京沿溯生物工程有限公司,南京,210095
2. 南京农业大学生命科学学院,南京,210095
基金项目:国家基础科学研究和人才培养基地基金
摘    要:创建了中国专利基因数据库NASDAP(http://nasdap.generank.org/).整合了专利序列、专利微阵列、专利基序和专利单核苷酸多态性(singlenucleotidepolymorphism,SNP)等专利对象,并实现对上述对象的BLAST检索或基序扫描服务.这为相关研究的立项、基因研发状态追踪以及基因专利申请和审批等工作提供了生物信息平台,并可为药物开发、疾病诊断和农业等生命科学相关研究的思路启发及知识产权战略制定等方面工作提供参考.

关 键 词:基因专利  专利基因  数据库  BLAST
收稿时间:02 23 2006 12:00AM
修稿时间:4/19/2006 1:08:31 PM

Construction of The National Bio-Sequence Database of Chinese Patent
YANG Lun and XU Lang-Lai.Construction of The National Bio-Sequence Database of Chinese Patent[J].Progress In Biochemistry and Biophysics,2006,33(8):800-803.
Authors:YANG Lun and XU Lang-Lai
Institution:1.College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China; 2.Wanjing YeSu Bio-engincering Co. Ltd., Nanjing 210095, China
Abstract:There were neither available database nor deep investigation on gene patents or patented genes in China before.But the National Bio-Sequence Database of Chinese Patent(NASDAP,http://nasdap.generank.org/),comprising 123 218 patented bio-sequences within 8 563 Chinese patents,has been constructed now.Genes,microarrays,single nucleotide polymorphisms(SNPs),motifs and any other objects of Chinese patent are involved in,and BLAST-based search or motif scan are carried out to navigate these objects,which can serve as an indispensable bioinformatics platform for setting up of research work,tracing of the advancement in patented genes and facilitating the decision of both applicants and assigners of gene patent.Such platform also gives comprehensive consults on drawing intellectual property strategies in the areas of pharmaceutics,diagnostics and agriculture.
Keywords:gene patent  patented gene  database  BLAST  
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