| 铁调素调节蛋白(HJV)———一个新的铁代谢调节蛋白 |
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| 引用本文： | 钱忠明,王 琴,徐又佳,柯 亚.铁调素调节蛋白(HJV)———一个新的铁代谢调节蛋白[J].生物化学与生物物理进展,2006,33(3):226-230. |
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| 作者姓名： | 钱忠明 王 琴 徐又佳 柯 亚 |
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| 作者单位： | 香港理工大学应用生物化学系铁代谢实验室,国家中药与分子药理学重点实验室(深圳),九龙,中国香港 |
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| 基金项目： | 欧盟科技部资助项目;国家重点实验室基金 |
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| 摘 要： | 铁调素调节蛋白 (hemojuvelin，HJV) 是最近发现的一种重要的铁代谢调节蛋白. HJV基因突变是年轻型血色素沉着症 (Juvenile hemochromatosis，JH ) 的重要原因之一. 研究显示，HJV可能是一种极为重要的铁调素 (hepcidin) 表达的调节蛋白，通过参与铁调素表达的调节从而在铁代谢中发挥重要作用.
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| 关 键 词： | 铁代谢 铁调素调节蛋白(HJV) 年轻型血色素沉着症(JH) |
| 收稿时间： | 2005-10-18 |
| 修稿时间： | 2005-10-182005-11-28 |
Hemojuvelin(HJV): A Newly Discovered Regulating Protein of Iron Metabolism |
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| QIAN Zhong-Ming,WANG Qin,XU You-Jia and KE Ya.Hemojuvelin(HJV): A Newly Discovered Regulating Protein of Iron Metabolism[J].Progress In Biochemistry and Biophysics,2006,33(3):226-230. |
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| Authors: | QIAN Zhong-Ming WANG Qin XU You-Jia and KE Ya |
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| Institution: | Laboratory of Iron Metabolism, Department of Applied Biology and Chemical Technology, National Key Laboratory of Traditional Chinese Medicine and Molecular Pharmacology (Shenzhen), The Hong Kong Polytechnic University, Kowloon, Hong Kong, China;Laboratory of Iron Metabolism, Department of Applied Biology and Chemical Technology, National Key Laboratory of Traditional Chinese Medicine and Molecular Pharmacology (Shenzhen), The Hong Kong Polytechnic University, Kowloon, Hong Kong, China;Laboratory of Iron Metabolism, Department of Applied Biology and Chemical Technology, National Key Laboratory of Traditional Chinese Medicine and Molecular Pharmacology (Shenzhen), The Hong Kong Polytechnic University, Kowloon, Hong Kong, China;Laboratory of Iron Metabolism, Department of Applied Biology and Chemical Technology, National Key Laboratory of Traditional Chinese Medicine and Molecular Pharmacology (Shenzhen), The Hong Kong Polytechnic University, Kowloon, Hong Kong, China |
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| Abstract: | |
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| Keywords: | iron metabolism hemojuvelin hereditory hemochormatosis |
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