| 刺激响应型纳米载体在肿瘤诊疗中的研究进展 |
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| 引用本文： | 田浩,赵鹏飞,郑明彬,马爱青,罗震宇,陈世春,鲁澄宇,蔡林涛.刺激响应型纳米载体在肿瘤诊疗中的研究进展[J].生物化学与生物物理进展,2018,45(6):593-600. |
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| 作者姓名： | 田浩 赵鹏飞 郑明彬 马爱青 罗震宇 陈世春 鲁澄宇 蔡林涛 |
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| 作者单位： | 广东医科大学东莞市药物设计与制剂技术重点实验室广东医科大学纳米药物制剂重点实验室;中国科学院深圳先进技术研究院中国科学院健康信息学重点实验室广东省纳米医药重点实验室深圳癌症纳米技术重点实验室 |
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| 基金项目： | 国家自然科学基金(21375141，81401509，81371679，21404115， 81401520，21701033)，重要国际科技合作项目(2015DFH50230)，广东省自然科学基金(2017A030313079，2017A030313726)，东莞社会科技发展项目(2015108101019)，中国博士后基金面上项目(2017M612803)和广东医科大学科研基金面上培育项目(M2016006)资助 |
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| 摘 要： | 刺激响应型纳米载体是通过对外界刺激响应而产生相应结构或理化性质变化的纳米智能载药体系,具有避免药物过早泄露,提高病灶药物浓度的特点,目前已成为肿瘤诊断和治疗领域的研究热点,广泛用于控制药物的呈递和释放.本文从温度、磁场、超声、光、pH等外源和内源刺激角度,阐述了智能响应型纳米载体近年来在肿瘤诊疗领域的研究进展.
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| 关 键 词： | 刺激响应，药物释放，纳米载体，药物传递，肿瘤 |
| 收稿时间： | 2017/10/20 0:00:00 |
| 修稿时间： | 2018/4/25 0:00:00 |
Research Progress of Stimuli Responsive Nanocarriers in Diagnosis and Treatment of Cancer |
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| TIAN Hao,ZHAO Peng-Fei,ZHENG Ming-Bin,MA Ai-Qing,LUO Zhen-Yu,CHEN Shi-Chun,LU Cheng-Yu and CAI Lin-Tao.Research Progress of Stimuli Responsive Nanocarriers in Diagnosis and Treatment of Cancer[J].Progress In Biochemistry and Biophysics,2018,45(6):593-600. |
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| Authors: | TIAN Hao ZHAO Peng-Fei ZHENG Ming-Bin MA Ai-Qing LUO Zhen-Yu CHEN Shi-Chun LU Cheng-Yu and CAI Lin-Tao |
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| Institution: | Key Laboratory for Nanomedicine of Guangdong Medical University, Dongguan Key Laboratory of Drug Design and Formulation Technology, Guangdong Medical University, Dongguan 523808, China; CAS Key of Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China,CAS Key of Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China,Key Laboratory for Nanomedicine of Guangdong Medical University, Dongguan Key Laboratory of Drug Design and Formulation Technology, Guangdong Medical University, Dongguan 523808, China; CAS Key of Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China,Key Laboratory for Nanomedicine of Guangdong Medical University, Dongguan Key Laboratory of Drug Design and Formulation Technology, Guangdong Medical University, Dongguan 523808, China; CAS Key of Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China,CAS Key of Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China,Key Laboratory for Nanomedicine of Guangdong Medical University, Dongguan Key Laboratory of Drug Design and Formulation Technology, Guangdong Medical University, Dongguan 523808, China,Key Laboratory for Nanomedicine of Guangdong Medical University, Dongguan Key Laboratory of Drug Design and Formulation Technology, Guangdong Medical University, Dongguan 523808, China and CAS Key of Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China |
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| Abstract: | |
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| Keywords: | stimuli responsive drug release nanocarriers drug delivery cancer |
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