| 功能基因组学的研究内容与方法 |
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| 引用本文： | 赵剑华,王秀琴,刘芝华,吴旻.功能基因组学的研究内容与方法[J].生物化学与生物物理进展,2000,27(1):6-8. |
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| 作者姓名： | 赵剑华 王秀琴 刘芝华 吴旻 |
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| 作者单位： | 中国医学科学院中国协和医科大学肿瘤研究所,分子肿瘤学国家重点实验室,北京,100021 |
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| 摘 要： | 基因组学的研究已从结构基因组学转向功能基因组学.综述了功能基因组学研究的内容和方法，主要包括应用微点阵、基因表达系列分析(SAGE)、蛋白质组、生物信息学等方法来研究基因组表达概况、基因组多样性、模式生物体等.
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| 关 键 词： | 人类基因组计划，功能基因组学，蛋白质组学，模式生物体，生物信息学 |
| 收稿时间： | 1999/5/24 0:00:00 |
| 修稿时间： | : |
Content and Methods of Functional Genomics |
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| ZHAO Jian-Hu,WANG Xiu-Qin,LIU Zhi-Hua and WU Min.Content and Methods of Functional Genomics[J].Progress In Biochemistry and Biophysics,2000,27(1):6-8. |
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| Authors: | ZHAO Jian-Hu WANG Xiu-Qin LIU Zhi-Hua and WU Min |
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| Institution: | National Laboratory of Molecular Oncology, Institute of Oncology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China;National Laboratory of Molecular Oncology, Institute of Oncology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China;National Laboratory of Molecular Oncology, Institute of Oncology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China;National Laboratory of Molecular Oncology, Institute of Oncology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China |
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| Abstract: | The main direction of study in genomics has been transferred from structural genomics to functional genomics. Content and methods of functional genomics are reviewed, including gene expression profile, genomic diversity, model organism,genomic comparation and evolution studied by microarray, serial analysis of gene expression, proteomics, bioinformatics , and so on. |
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| Keywords: | human genome project functional genomics proteomics model organism bioinformatics |
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