| DNA生物传感器进展 |
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| 引用本文： | 翟俊辉,崔红,杨瑞馥.DNA生物传感器进展[J].生物化学与生物物理进展,1997,24(2):112-115. |
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| 作者姓名： | 翟俊辉 崔红 杨瑞馥 |
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| 作者单位： | 军事医学科学院微生物流行病研究所，北京 100071;军事医学科学院微生物流行病研究所，北京 100071;军事医学科学院微生物流行病研究所，北京 100071 |
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| 摘 要： | 近几年来，酶传感器、免疫传感器及微生物传感器等发展较为成熟，而DNA生物传感器的研究相对较少.文章从核酸杂交的原理出发介绍了DNA生物传感器的工作原理，举例说明了电化学、光学和声学等几种典型的DNA生物传感器，指出了其固有的优缺点，肯定了DNA传感器发展前景.
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| 关 键 词： | DNA生物传感器 核酸杂交 探针 压电晶体 光纤 |
| 收稿时间： | 1996/4/18 0:00:00 |
| 修稿时间： | 1996/7/12 0:00:00 |
Advances in DNA Biosensors |
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| ZHAI Junhui,CUI Hong and YANG Ruifu.Advances in DNA Biosensors[J].Progress In Biochemistry and Biophysics,1997,24(2):112-115. |
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| Authors: | ZHAI Junhui CUI Hong and YANG Ruifu |
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| Institution: | Institute of Microbiology and Epidemiology, Beijing 100071, China;Institute of Microbiology and Epidemiology, Beijing 100071, China;Institute of Microbiology and Epidemiology, Beijing 100071, China |
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| Abstract: | Most recent researches have concentrated on the rapid development of enzymesensors, immunosensors and microbial biosensors, whereas the studies about the DNA biosensor are relatively scarce. The principles of DNA sensor based on the principle of nucleic acid hybridization are reviewed. Several kinds of DNA sensors such as electrochemical, optical, acoustic and piezoelectric are introduced and compared, the high specificity and low responsibility of DNA sensor are also discussed. Generally speaking, DNA biosensor has a more prospective future. |
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| Keywords: | DNA biosensor nucleic acid hybridization probe piezoelectric optical fiber |
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