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Long-Term Epidemiology of Streptococcus pneumoniae Serogroup 6 in a Region of Southern Europe with Special Reference to Serotype 6E
Authors:José M Marimón  María Ercibengoa  Esther Tamayo  Marta Alonso  Emilio Pérez-Trallero
Institution:1. Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain;2. Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain;3. Faculty of Medicine, University of the Basque Country, UPV/EHU, San Sebastián, Spain;Faculdade de Medicina de Lisboa, PORTUGAL
Abstract:Streptococcus pneumoniae serotype 6E has recently been described, but its long-term epidemiology is not well known. From 1981–2013, 704 serogroup 6 clinical isolates were obtained in Gipuzkoa, Basque Country, Spain. All invasive and one in four non-invasive isolates were included. Overall, 75, 97, 51 and 45 serotypes 6A, 6B, 6C and 6E isolates, respectively, were detected. No serotype 6D isolates were identified. The prevalence of serotypes 6E and 6B, but not that of serotypes 6A and 6C, declined after the introduction of pneumococcal conjugate vaccines. Serotype 6E isolates showed the highest resistance rate. Most serotype 6E isolates were ST90.
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