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PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress |
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| Authors: | D Mazzà P Infante V Colicchia A Greco R Alfonsi M Siler L Antonucci A Po E De Smaele E Ferretti C Capalbo D Bellavia G Canettieri G Giannini I Screpanti A Gulino L Di Marcotullio |
| Institution: | 1.Department of Molecular Medicine, University of Rome La Sapienza, Rome, Italy;2.Center for Life NanoScience at LaSapienza, Istituto Italiano di Tecnologia, Italy;3.Foundation for Liver Research, Institute of Hepatology, London, UK;4.Department of Experimental Medicine, University of Rome La Sapienza, 00161 Rome, Italy;5.Neuromed Institute, Pozzilli 86077, Italy |
| Abstract: | |
| Keywords: | Hedgehog signaling ubiquitylation PCAF p53 medulloblastoma |