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12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells
Authors:Sriram Krishnamoorthy  Rongxian Jin  Krishna Rao Maddipati  Daotai Nie  Gilles Pagès  Kenneth V Honn
Institution:a Department of Pathology, Wayne State University School of Medicine, and, Detroit, MI 48202, USA
b Barbara Ann Karmanos Cancer Institute, Detroit, MI 48202, USA
c Centre de Biochimie, CNRS-UMR 6543, Universite de Nice, Parc Valrose, 06108 Nice, France
Abstract:
Keywords:LOX  Lipoxygenase  HETE  Hydroxyeicosatetraenoic Acid  HIF-1α  Hypoxia Inducible Factor-1α  VEGF  Vascular Endothelial Growth Factor  HRE  Hypoxia Response Element  PI3K  Phospho Inositide 3 Kinase  PTEN  Phosphatase and Tensin homolog deleted on chromosome ten  mTOR  mammalian Target of Rapamycin  GLUT-1  Glucose Transporter-1
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