The effect of binding divalent metal ions on the conformation of human angiotensin-II in solution as probed by nuclear and electron paramagnetic resonance investigations |
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| Authors: | Riccardo Basosi Elena Gaggelli Gianni Valensin |
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| Institution: | Institute of General Chemistry, University of Siena, Siena, Italy |
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| Abstract: | The interaction between human angiotensin-II and Mn(II) ions in water solution has been deline-ated by nmr and esr experiments. A pH-dependent binding interaction with the imidazole moiety of His 6 has been shown, ratifying the suggestion that His 6 is involved in intramolecular structuring within the peptide molecule. |
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