Complete Genome Sequence of a J Subgroup Avian Leukosis Virus Isolated from Local Commercial Broilers |
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| Authors: | Hongxin Li Chunyi Xue Jun Ji Shuang Chang Huiqin Shang Lingjun Zhang Jingyun Ma Yingzuo Bi Qingmei Xie |
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| Institution: | aCollege of Animal Science, South China Agricultural University, Guangzhou, China;bState Key Laboratory of Biocontrol, College of Life Sciences, Sun Yat-Sen University, Guangzhou, China;cCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China;dDepartment of Animal Science, Michigan State University, East Lansing, Michigan, USA |
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| Abstract: | Subgroup J avian leukosis virus (ALV-J) isolate GDKP1202 was isolated from a 50-day-old local yellow commercial broiler in the Guangdong province of China in 2012. Here we report the complete genomic sequence of the GDKP1202 isolate, which caused high mortality, serious growth suppression, thymic atrophy, and liver enlargement in commercial broilers. A novel potential binding site (5′-GGCACCTCC-3′) for c-myb was identified in the GDKP1202 genome. These findings will provide additional insights into the molecular characteristics in the genomes and pathogenicity of ALV-J. |
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