| 昆虫杆状病毒表达载体系统的研究及应用 |
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| 引用本文： | 刘永平,王方海,苏志坚,李广宏,庞义.昆虫杆状病毒表达载体系统的研究及应用[J].昆虫知识,2006,43(1):1-5. |
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| 作者姓名： | 刘永平 王方海 苏志坚 李广宏 庞义 |
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| 作者单位： | 1. 中山大学昆虫研究所生物防治国家重点实验室,广州,510275
2. 暨南大学药学院,广州,510632 |
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| 基金项目： | 中国科学院资助项目;广东省科技攻关项目;广东省肇庆市科技计划 |
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| 摘 要： | 昆虫杆状病毒表达载体系统具有表达水平高、表达产物可进行翻译后加工,并可通过感染昆虫幼虫而实现大规模低成本生产基因工程产品,该系统的建立和发展,被誉为20世纪80年代真核表达研究领域的一个重大进展。文章介绍了该系统的产生、发展和技术原理,同时概述了该系统在基础研究、医药和农林业等领域的应用情况。
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| 关 键 词： | 昆虫杆状病毒表达载体系统 基础研究 医药 农林业 |
| 收稿时间： | 12 28 2004 12:00AM |
| 修稿时间： | 02 21 2005 12:00AM |
Progress of studies and application on baculovirus expression vector system |
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| LIU Yong-Ping,WANG Fang-Hai,SU Zhi-Jian,LI Guang-Hong,PANG Yi.Progress of studies and application on baculovirus expression vector system[J].Entomological Knowledge,2006,43(1):1-5. |
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| Authors: | LIU Yong-Ping WANG Fang-Hai SU Zhi-Jian LI Guang-Hong PANG Yi |
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| Institution: | 1. lnstitute of Entomology, State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, China; 2. School of Pharmaceutical Sciences, Jinan University, Guangzhou 510632, China |
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| Abstract: | As one of the four expression vector systems,insect baculovirus expression vector systems(BEVS) has many advantages,such as high yield,proper post-translation modification,large-scale production of the recombinant products with low cost by infection of the insect larvae.This system was regarded as a great breakthrough in the field of eukaryotic expression in the(80's) of the 20th century.This paper reviews the origination,development,and technological principle of BEVS;its potential applications in the fields of medicine,agriculture,forestry,and other basic sciences were also discussed in this paper. |
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| Keywords: | BEVS foundational research medicine agriculture and forestry |
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