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The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation
Authors:Florian Sparber  Corinne De Gregorio  Simone Steckholzer  Filipa M Ferreira  Tamas Dolowschiak  Fiorella Ruchti  Florian R Kirchner  Sarah Mertens  Immo Prinz  Nicole Joller  Thorsten Buch  Martin Glatz  Federica Sallusto  Salomé LeibundGut-Landmann
Institution:1. Section of Immunology, Vetsuisse Faculty, University of Zürich, Zürich 8057, Switzerland;2. Institute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona 6500, Switzerland;3. Institute of Laboratory Animal Science, University of Zürich, Schlieren 8952, Switzerland;4. Institute of Experimental Immunology, University of Zürich, Zürich 8057, Switzerland;5. Institute of Immunology, Hannover Medical School, Hannover 30625, Germany;6. Department of Dermatology, University and University Hospital of Zürich, Zürich 8091, Switzerland;7. Institute of Microbiology, ETH Zürich, Zürich 8093, Switzerland
Abstract:
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  • Keywords:skin microbiota  fungal commensalism  atopic dermatitis  interleukin-17  γδ T cells  Th17  skin immunity  interleukin-23  inflammation
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