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苯并(a)芘对大弹涂鱼肝脏过氧化氢酶活性的影响
引用本文:冯涛,郑微云,郭祥群,陈荣.苯并(a)芘对大弹涂鱼肝脏过氧化氢酶活性的影响[J].生态学杂志,2001,20(5):73-75.
作者姓名:冯涛  郑微云  郭祥群  陈荣
作者单位:1. 厦门大学环境科学研究中心
2. 厦门大学化学系
基金项目:高等学校博士学科点专项科研基金项目(49876029)资助.
摘    要:过氧化氢酶 (CAT)是生物体内一种含巯基 ( -SH)的抗氧化酶 ,可与谷胱甘肽过氧化物酶一起 ,清除超氧化物歧化酶歧化超氧阴离子自由基(O2 - )产生的过氧化氢 (H2 O2 ) ,进而阻断可产生活性极高的羟自由基 (OH)的Haber Weiss反应 :M O2 - H2 O2 →M2 OH OH O2 (M 为金属离子 ) ,因而在生物体的抗氧化防御系统中占有重要地位1 2 ] 。研究表明 ,包括CAT在内的抗氧化防御系统的成分可由于氧化污染的胁迫而发生改变 ,尝试以这些抗氧化防御系统成分的变化作为氧化胁迫的生物指标的研究正在成为毒理学研究的…

关 键 词:苯并(a)芘  大弹涂鱼  肝脏  过氧化氢酶  酶活性  水污染  毒理
文章编号:1000-4890(2001)05-0073-03
修稿时间:2000年7月24日

Effects of Catalase Activities in the Liver of Boleophthalmus Pectinirostris with Benzo(a) Pyrene Exposure
Abstract.Effects of Catalase Activities in the Liver of Boleophthalmus Pectinirostris with Benzo(a) Pyrene Exposure[J].Chinese Journal of Ecology,2001,20(5):73-75.
Authors:Abstract
Abstract:Changes of catalase(CAT) activities in the liver of Boleophthalmus pectinirostris with benzo(a)pyrene(BaP) exposure are detected in experimental condition. The results show that there is no significant changes for CAT activities in control group and 0.05mg*L-1 BaP group with prolonged exposure (P>0.05), whereas they are depressed significantly at concentration of 0.5mg*L-1(P≤0.05). In 3 days exposure, CAT activities decrease significantly with the increase of BaP concentration (P≤0.05). This might indicate that exposure to higher BaP concentrations might have toxic effect to fishes. The activities of CAT increase significantly to control level after BaP was removed. It turned out that the physiological modulatary mechanism still existed in the liver of Boleophthalmus pectinirostris. All the results show that CAT activity might be suitable to be the bioindicator of BaP exposure.
Keywords:benzo(a) pyrene(BaP)    Boleophthalmus pectinirostris    catalase (CAT)  
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