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The lack of histological changes of CDMA cellular phone‐based radio frequency on rat testis
Authors:Hae‐June Lee  Jeong‐Ki Pack  Tae‐Hong Kim  Nam Kim  Soo‐Yong Choi  Jae‐Seon Lee  Sung‐Ho Kim  Yun‐Sil Lee
Institution:1. Division of Radiation Effects, Korea Institute of Radiological and Medical Sciences, Seoul, Korea;2. Department of Radio Sciences and Engineering, College of Engineering, Choongnam National University, Daejon, Korea;3. School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Korea;4. Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea;5. College of Veterinary Medicine, Chonnam National University, Gwangju, Korea
Abstract:We examined the histological changes by radiofrequency (RF) fields on rat testis, specifically with respect to sensitive processes such as spermatogenesis. Male rats were exposed to 848.5 MHz RF for 12 weeks. The RF exposure schedule consisted of two 45‐min RF exposure periods, separated by a 15‐min interval. The whole‐body average specific absorption rate (SAR) of RF was 2.0 W/kg. We then investigated correlates of testicular function such as sperm counts in the cauda epididymis, malondialdehyde concentrations in the testes and epididymis, frequency of spermatogenesis stages, germ cell counts, and appearance of apoptotic cells in the testes. We also performed p53, bcl‐2, caspase 3, p21, and PARP immunoblotting of the testes in sham‐ and RF‐exposed animals. Based on these results, we concluded that subchronic exposure to 848.5 MHz with 2.0 W/kg SAR RF did not have any observable adverse effects on rat spermatogenesis. Bioelectromagnetics 31:528–534, 2010. © 2010 Wiley‐Liss, Inc.
Keywords:RF exposure  848  5   MHz  rat spermatogenesis
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