One week of exposure to 50 Hz, vertical magnetic field does not reduce urinary 6-sulphatoxymelatonin excretion of male wistar rats |
| |
Authors: | Bakos József Nagy Noémi Thuróczy György Szabó László D |
| |
Institution: | Department of Non-ionizing Radiation, National "Frédéric Joliot-Curie" Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary. |
| |
Abstract: | The effect of exposure to 100 or 50 microT, 50 Hz, vertical magnetic field on the excretion of 6-sulphatoxymelatonin (6SM) in the nocturnal urine of rats was studied. Twelve male Wistar rats were kept under 12:12 hr light:dark conditions. The nocturnal urine of animals was collected in metabolic cages over 4 consecutive weeks. The concentration of 6SM in the rat urine was measured by 125I radioimmunoassay and normalized to creatinine concentration. After the first week of urine collection, 6 rats were exposed to 100 microT or 50 microT flux density magnetic fields (MF) for 8 hr daily for 1 week. It was found that the excretion of the primary metabolite of melatonin in the urine, 6SM, did not show statistically significant changes during and after magnetic field exposure. |
| |
Keywords: | extremely low frequency melatonin metabolite nocturnal urine |
本文献已被 PubMed 等数据库收录! |
|