| 细菌的噬菌体感染抗性机制 |
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| 引用本文： | 徐嘉良,阚飙.细菌的噬菌体感染抗性机制[J].生物技术通讯,2013(3):409-413. |
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| 作者姓名： | 徐嘉良 阚飙 |
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| 作者单位： | 中国疾病预防控制中心传染病预防控制所、传染病预防控制国家重点实验室,北京102206 |
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| 基金项目： | 国家科技重大专项（2012ZX10004215,2008ZX10004-008） |
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| 摘 要： | 噬菌体广泛存在于生态环境中。细菌在与噬菌体长期的共进化过程中，衍化出了多种针对噬茵体感染的抗性机制。我们从宿主菌的抑制吸附、阻止噬菌体DNA注入、切断噬菌体DNA和影响其功能及流产感染等方面，对宿主菌抵抗噬菌体感染的机制进行了综述。
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| 关 键 词： | 噬菌体 感染 抗性 |
Bacterial Resistance Mechanisms to Bacteriophage |
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| XU Jia-Liang,KAN Biao.Bacterial Resistance Mechanisms to Bacteriophage[J].Letters in Biotechnology,2013(3):409-413. |
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| Authors: | XU Jia-Liang KAN Biao |
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| Institution: | (National Institute for Communicable Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing 102206, China) |
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| Abstract: | Phages widely exist in ecological environment. In the long-term co-evolution of phage-bacteria, bacteria evolved series of resistance mechanisms. Here mechanisms involved in adsorption inhibition, preventing phage DNA injection, cutting DNA and interference in the function of DNA and abortive infection were reviewed. |
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| Keywords: | bacteriophage infection resistance |
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