| 志贺菌毒力检测的常用方法 |
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| 引用本文： | 谢超华,朱力,王恒樑.志贺菌毒力检测的常用方法[J].生物技术通讯,2009,20(5):738-741. |
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| 作者姓名： | 谢超华 朱力 王恒樑 |
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| 作者单位： | 军事医学科学院生物工程研究所,北京,100071 |
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| 摘 要： | 志贺菌属的细菌以人类为特异性宿主,感染人类肠上皮细胞,多导致痉挛性腹痛、腹泻、发烧等症状,是细菌性痢疾最为常见的病原菌。志贺菌的致病机理主要由其Ⅲ型分泌系统调节。志贺菌侵袭力的高低及毒力强弱决定了其致病性的强弱。我们简要介绍志贺菌属细菌的毒力检测方法。
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| 关 键 词： | 志贺菌属 毒力 侵袭力 检测 |
Methods for Dectecting the Virulence of Shigella spp. |
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| XIE Chao-Hua,ZHU Li,WANG Heng-Liang.Methods for Dectecting the Virulence of Shigella spp.[J].Letters in Biotechnology,2009,20(5):738-741. |
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| Authors: | XIE Chao-Hua ZHU Li WANG Heng-Liang |
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| Institution: | Liang (Beijing Insitute of Biotechnology, Beijing 100071, China) |
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| Abstract: | Shigella spp.is human host-specific pathogens that infects intestinal epithelial cells.It is the causative agent of dysentery which is followed by cramps,diarrhea and fever.Its pathogenesis is mediated by a type Ⅲ secretion system.The pathogenicity of Shigella is determined by its invasiveness and virulence.This article is a review about how to detect the virulence of the Shigella. |
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| Keywords: | Shigella virulence invasiveness detection |
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