首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Synovial tissues concentrate secreted APRIL
Authors:Cem Gabay  Veit Krenn  Carine Bosshard  Alexander Christian Seemayer  Carlo Chizzolini and Bertrand Huard
Institution:(1) Division of Rheumatology, University Hospitals, 4 rue Gabrielle Perret-Gentil, Geneva, CH, 1211, Switzerland;(2) Department of Pathology-Immunology, Faculty of Medicine, 1 rue Michel Servet, Geneva, CH, 1211, Switzerland;(3) Cytology and Molecular Diagnostic, Histology Center, Max Planck Street, Trier, D-54296, Germany;(4) Division of Hematology, 4 rue Gabrielle Perret-Gentil, Geneva, CH, 1211, Switzerland;(5) Department of Pathology, Faculty of Medicine, 1 rue Michel Servet, Geneva, CH, 1211, Switzerland;(6) Current address: Rheumatology, University Hospitals, 46 rue du Bugnon, Lausanne, CH, 1011, Switzerland;(7) Division of Immunology and Allergy, 4 rue Gabrielle Perret-Gentil, Geneva, CH, 1211, Switzerland
Abstract:

Introduction  

A proliferation-inducing ligand (APRIL) from the TNF family, owing to its role in the generation and survival of plasma cells (PCs), is currently targeted for rheumatoid arthritis (RA) treatment. However, little is known about APRIL expression in RA lesions, hampering our understanding of the way APRIL may modulate this autoimmune disease.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号