几种萝卜提取物在组织培养细胞中的抗病毒感染活性

我们曾报道,白萝卜提取物是一种干扰素诱生剂,对致死性病毒感染动物有很显著的保护作用。 本实验在组织培养单层细胞上测试了十字花科萝卜属几种萝卜栽培变种,包括“心里美”、“卫青”、“象牙白”(白萝卜)和伞形科胡萝卜提取物的抗病毒感染活性。 萝卜提取物的制备和定量方法,按文献进行。萝卜提取物在组织培养单层细胞上抑

ANTIVIRAL ACTIVITY OF EXTRACTS OF ROOTS OF RAPHANUS SATIVUS-CULTIVARS AND DAUCUS CAROTA IN VITRO

The extracts of roots of Raphanus sativus-cultivars ( ie. cv. "Xin limei", cv. "Wei qing" and cv."Xiang ya bai)and Daucus carota var. sativa were found to have antiviral activity in vitro by the authors.Tests of antiviral activity of the extracts were undertaken in primary rabbit kidney cell-VSV system. The extracts of roots from three R. sativus-cultivars, in particular cv. "Xin li mei" and cv."Wei qing", were highly active whereas the extract of root of D.carota var. sativa was relatively lower active.Development of resistance to the virus infection requires an interaction between the extracts tested and the celi and a time period is required fo the development of resistance.We had proved that extract of root of R,sativus cv. "Xiang ya bai" is an interferon inducer. So, it is probable that extracts from roots of other R, sativus-cultivars and D. carota var. sativa should be interferon inducer also.Finally, the practical meanings of the findings were discussed.