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丹参四倍体优良品系有效成分的含量测定及药理学试验
引用本文:朱丹妮,高山林,卞云云,程心玟.丹参四倍体优良品系有效成分的含量测定及药理学试验[J].植物资源与环境学报,2001,10(2):7-10.
作者姓名:朱丹妮  高山林  卞云云  程心玟
作者单位:中国药科大学,江苏南京 210038
基金项目:国家科技部"九五”国家级重点科技成果推广项目(97100504A)的一部分
摘    要:运用HPLC法测定丹参(Sabuia miltiorrhiza Bunge)同源四倍体优良品系61-2-22及安徽、江苏和陕西产丹参不同部位、不同生长年限的有效成分(3种丹参酮和2种水溶性酚酸)含量。丹参品系61-2-22的有效成分含量明显高于其他产地丹参的含量;根中有效成分含量明显高于茎和叶的含量;丹参酮和丹参素的含量呈明显相关。初步药理实验结果表明,在相同剂量下,优良品系61-2-22具有更好的药理活性。

关 键 词:丹参  同源四倍体  丹参酮类  丹参素  HPLC  含量测定  药理学中药材  有效成分
文章编号:1004-0978(2001)02-0007-04

Determination of effective constituents in autotetraploid elite line of Salvia miltiorrhiza Bunge and
ZHU Dan\|ni,GAO Shan\|lin,BIAN Yun\|yun,CHENG Xin\|min.Determination of effective constituents in autotetraploid elite line of Salvia miltiorrhiza Bunge and[J].Journal of Plant Resources and Environment,2001,10(2):7-10.
Authors:ZHU Dan\|ni  GAO Shan\|lin  BIAN Yun\|yun  CHENG Xin\|min
Abstract:Three kinds of tanshinone and two kinds of water\|soluble phenolic\|acid in different parts of plants and different growth years of autotetraploid elite line 61\|2\|22 and different localities of \%Salvia miltiorrhiza \%Bunge were determined by HPLC. The results indicated that the contents of effective constituents in the new autotetraploid of \%Salvia miltiorrhiza \%were significantly higher than that in other samples. The contents of effective constituents in roots were significantly higher than that in stems and leaves. The content of tanshinone was closely related to the content of danshensu in all tested materials. Primary pharmacological experiments indicated that the new autotetraploid line of \%Salvia miltiorrhiza \%showed more active pharmacological effects.
Keywords:Salvia miltiorrhiza Bunge  autotetraploid  tanshinone  danshensu  HPLC
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