Regulation of glucose-6-p dehydrogenase synthesis in rat epididymal fat pads. |
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Authors: | R G Wolfe R Nakayama D Holten |
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Institution: | Department of Biochemistry University of California Riverside, California 92521 USA |
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Abstract: | The relative rate of synthesis of glucose-6-P dehydrogenase increases up to 8-fold when fasted rats are fed a 60% carbohydrate, fat-free diet for 3 days but the specific activity of the enzyme only increases 2 to 3 fold. This suggests that the high carbohydrate diet also causes a 2 to 3 fold increase in the rate of glucose-6-P dehydrogenase degradation. The nutritional induction of this enzyme in adipose tissue is primarily due to a large increase in the rate of its synthesis. |
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Keywords: | SDS sodium dodecyl sulfate |
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