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Examination of adipose depot-specific PPAR moieties |
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| Authors: | MV Dodson JL Vierck LL Guan SP Poulos Z Jiang |
| Institution: | a Department of Animal Sciences, Washington State University, Pullman, WA 99164, USA b USDA-ARS, Richard B. Russell Agricultural Research Station, Athens, GA 30604, USA c Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, T6G 2P5 Canada d The Hartz Mountain Corporation, Secaucus, NJ 07094, USA e The Coca-Cola Company, Research and Technology, Atlanta, GA 30313, USA f Agriculture and Agri-Food Canada Research Centre, Lethbridge, CA T1J 4B1, USA |
| Abstract: | Molecular mechanisms of peroxisome proliferator activated receptors (PPARs) are being defined rapidly, as illustrated by the volume of papers published. Much of the research is directed towards a clinical end-point/application; however, the non-homogeneous nature of adipose depots in laboratory animals is spurring similar research in domestic meat animals (such as beef cattle). Moreover, the size of adipose depots in meat animals remains an attractive feature for using them to obtain cells for PPAR research. Examination of meat-animal depot-specific PPAR moieties may provide novel information about adipocyte regulation that might be extrapolated to all animals. |
| Keywords: | PPAR Adipose depot Large animals |
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