Coordinate regulation of DNA methyltransferase expression during oogenesis |
| |
| Authors: | Diana Lucifero Sophie La Salle Déborah Bourc'his Josée Martel Timothy H Bestor Jacquetta M Trasler |
| |
| Institution: | (1) Montreal Children's Hospital Research Institute and Departments of Pediatrics Human Genetics, and Pharmacology & Therapeutics, McGill University, H3H 1P3 Montreal, Quebec, Canada;(2) Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, 10032 New York, New York, USA |
| |
| Abstract: | Background Normal mammalian development requires the action of DNA methyltransferases (DNMTs) for the establishment and maintenance of
DNA methylation within repeat elements and imprinted genes. Here we report the expression dynamics of Dnmt3a and Dnmt3b, as well as a regulator of DNA methylation, Dnmt3L, in isolated female germ cells. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
