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芒果核仁的化学成分及其抑菌活性
引用本文:梁耀光,徐巧林,谢海辉,周艳阳,魏孝义.芒果核仁的化学成分及其抑菌活性[J].热带亚热带植物学报,2010,18(4):445-448.
作者姓名:梁耀光  徐巧林  谢海辉  周艳阳  魏孝义
作者单位:1. 中国科学院华南植物园,广州,510650
2. 日本丸善制药株式会社,广岛,729-3102
基金项目:中国科学院知识创新工程重要方向项目 
摘    要:从杧果(Mangifera indica L.)果实核仁中分离得到6种化合物。经光谱分析及与文献对照,分别鉴定为没食子酸(1)、没食子酸甲酯(2)、没食子酸乙酯(3)、间-二没食子酸甲酯(4)、对羟基苯甲酸(5)和丁二酸单甲酯(6),它们均为首次从芒果核中获得。用琼脂平板稀释法测定了化合物1~5对7种细菌和4种真菌生长的抑制活性。结果表明,化合物1对金黄色葡萄球菌(Staphylococcus aureus)、表皮葡萄球菌(S. epidermidis)、干燥棒状杆菌(Corynebacterium xerosis)和藤黄微球菌(Micrococcus luteus)的最小抑制浓度(MIC)为50~100 µg mL-1,化合物4对绿脓杆菌(Pseudomonas aeruginosa)有抑制活性。

关 键 词:杧果  核仁  抑菌活性  没食子酸  间-二没食子酸甲酯
收稿时间:2009/12/15 0:00:00
修稿时间:2010/3/20 0:00:00

Chemical Constituents from Mango Seed Kernels and Their Antimicrobial Activity
LIANG Yao-guang,XU Qiao-lin,XIE Hai=hui,ZHOUse Yan-yang and WEI Xiao-yi.Chemical Constituents from Mango Seed Kernels and Their Antimicrobial Activity[J].Journal of Tropical and Subtropical Botany,2010,18(4):445-448.
Authors:LIANG Yao-guang  XU Qiao-lin  XIE Hai=hui  ZHOUse Yan-yang and WEI Xiao-yi
Institution:South China Botanical Garden, Chinese Academy of Science,South China Botanical Garden, Chinese Academy of Sciences,South China Botanical Garden, Chinese Academy of Science,Maruzen Pharmaceuticals Co., Ltd, Japan,South China Botanical Garden, Chinese Academy of Sciences
Abstract:Six compounds were isolated from mango (Mangifera indica L.) seed kernels. On the basis of spectral data and references, they were identified as gallic acid (1), methyl gallate (2), ethyl gallate (3), methyl m-digallate (4), p-hydroxybenzoic acid (5), and succinic acid monomethyl ester (6), which were obtained from mango seeds for the first time. Antimicrobial activity of compounds 1~5 against seven bacterial and four fungal strains was determined by using the agar plate dilution method. The results showed that the minimal inhibitory concentration (MIC) values of compound 1 against Staphylococcus aureus, S. epidermidis, Corynebacterium xerosis, and Micrococcus luteus were 50~100 µg mL-1, and compound 4 exhibited inhibitory activity against Pseudomonas aeruginosa.
Keywords:Mangifera indica L    Seed kernel  Antimicrobial activity  Gallic acid  Methyl m-digallate
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